Plant Transcription Factor Database
Previous version: v3.0
Sesamum indicum
NF-YA Family
Species TF ID Description
XP_011075221.1NF-YA family protein
XP_011077810.1NF-YA family protein
XP_011077811.1NF-YA family protein
XP_011080343.1NF-YA family protein
XP_011080345.1NF-YA family protein
XP_011080346.1NF-YA family protein
XP_011080347.1NF-YA family protein
XP_011080348.1NF-YA family protein
XP_011080349.1NF-YA family protein
XP_011080350.1NF-YA family protein
XP_011080351.1NF-YA family protein
XP_011080352.1NF-YA family protein
XP_011085206.1NF-YA family protein
XP_011090023.1NF-YA family protein
XP_011090024.1NF-YA family protein
XP_011090025.1NF-YA family protein
XP_011093323.1NF-YA family protein
XP_011093324.1NF-YA family protein
XP_011093783.1NF-YA family protein
XP_011093784.1NF-YA family protein
XP_011093785.1NF-YA family protein
XP_011093786.1NF-YA family protein
XP_011094246.1NF-YA family protein
XP_011096680.1NF-YA family protein
XP_011096681.1NF-YA family protein
XP_011096682.1NF-YA family protein
XP_011096683.1NF-YA family protein
XP_011101386.1NF-YA family protein
XP_011101465.1NF-YA family protein
NF-YA Family Introduction

NF-Y transcription factors are likely found in all eukaryotes and have roles in the regulation of diverse genes (McNabb et al., 1995; Edwards et al., 1998; Maity and de Crombrugghe, 1998; Mantovani, 1999). In mammals, where their biochemistry is well described, the NF-Y transcription factor complex is composed of three unique subunits: NF-YA, NF-YB, and NF-YC. Assembly of the NF-Y heterotrimer in mammals follows a strict, stepwise pattern (Sinha et al., 1995, 1996). Initially, a heterodimer is formed in the cytoplasm between the subunits NF-YB and NF-YC. This dimer then translocates to the nucleus, where the third subunit, NF-YA, is recruited to generate the mature, heterotrimeric NF-Y transcription factor (Frontini et al., 2004; Kahle et al., 2005). Mature NF-Y binds promoters with the core pentamer nucleotide sequence CCAAT, and this can result in either positive or negative transcriptional regulation(Peng and Jahroudi, 2002, 2003; Ceribelli et al., 2008).

NF-YA proteins are characterized by the presence of Gln(Q)- and Ser/Thr(S/T)-rich NH2 termini, a subunit interaction domain (NF-YB/NF-YC interaction), and a DNA-binding domain (Olesen and Guarente, 1990; Maity and de Crombrugghe, 1992; Xing et al., 1993, 1994). The protein interaction and DNA binding domains are well conserved between plant and other eukaryote lineages.

Siefers N, Dang KK, Kumimoto RW, Bynum WE 4th, Tayrose G, Holt BF 3rd.
Tissue-specific expression patterns of Arabidopsis NF-Y transcription factors suggest potential for extensive combinatorial complexity.
Plant Physiol, 2009. 149(2): p. 625-41.
PMID: 19019982